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Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice

The cholinotrophic system, which is dependent upon nerve growth factor and its receptors for survival, is selectively vulnerable in Alzheimer's disease (AD). But, virtually nothing is known about how this deficit develops in relation to the hallmark lesions of this disease, amyloid plaques and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Perez, Sylvia E., He, Bin, Muhammad, Nadeem, Oh, Kwang-Jin, Fahnestock, Margaret, Ikonomovic, Milos, Mufson, Elliott J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014453/
https://ncbi.nlm.nih.gov/pubmed/20937383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.10.002
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