A new clustering method identifies multiple sclerosis‐specific T‐cell receptors

OBJECTIVE: To characterize T‐cell receptors (TCRs) and identify target epitopes in multiple sclerosis (MS). METHODS: Peripheral blood mononuclear cells were obtained from 39 MS patients and 19 healthy controls (HCs). TCR repertoires for α/β/δ/γ chains, TCR diversity, and V/J usage were determined by...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Hayashi, Fumie, Isobe, Noriko, Glanville, Jacob, Matsushita, Takuya, Maimaitijiang, Guzailiayi, Fukumoto, Shoko, Watanabe, Mitsuru, Masaki, Katsuhisa, Kira, Jun‐ichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818280/
https://ncbi.nlm.nih.gov/pubmed/33400858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51264
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