Praja1 RING‐finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP‐43 aggregate formation

Transactivation response DNA‐binding protein of 43 kDa (TDP‐43) is a major constituent of cytoplasmic aggregates in neuronal and glial cells in cases of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). We have previously shown neuronal cytoplasmic aggregate formation...

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Detalhes bibliográficos
Publicado no:Neuropathology
Main Authors: Watabe, Kazuhiko, Kato, Yoichiro, Sakuma, Miho, Murata, Makiko, Niida‐Kawaguchi, Motoko, Takemura, Taro, Hanagata, Nobutaka, Tada, Mari, Kakita, Akiyoshi, Shibata, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Australia, Ltd 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818255/
https://ncbi.nlm.nih.gov/pubmed/32686212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/neup.12694
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