Identification and characterisation of putative drug binding sites in human ATP-binding cassette B5 (ABCB5) transporter

The human ATP-binding cassette B5 (ABCB5) transporter, a member of the ABC transporter superfamily, is linked to chemoresistance in tumour cells by drug effluxion. However, little is known about its structure and drug-binding sites. In this study, we generated an atomistic model of the full-length h...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Tangella, Lokeswari P., Arooj, Mahreen, Deplazes, Evelyne, Gray, Elin S., Mancera, Ricardo L.
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817430/
https://ncbi.nlm.nih.gov/pubmed/33510870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.12.042
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