ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer

ABC member B5 (ABCB5) mediates multidrug resistance (MDR) in diverse malignancies and confers clinically relevant 5-fluorouracil resistance to CD133-expressing cancer stem cells in human colorectal cancer (CRC). Because of its recently identified roles in normal stem cell maintenance, we hypothesize...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Guo, Qin, Grimmig, Tanja, Gonzalez, Gabriel, Giobbie-Hurder, Anita, Berg, Gretchen, Carr, Nolan, Wilson, Brian J., Banerjee, Pallavi, Ma, Jie, Gold, Jason S., Nandi, Bisweswar, Huang, Qin, Waaga-Gasser, Ana Maria, Lian, Christine G., Murphy, George F., Frank, Markus H., Gasser, Martin, Frank, Natasha Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052213/
https://ncbi.nlm.nih.gov/pubmed/29789423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003187
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