Unexpected Transcriptional Programs Contribute to Hippocampal Memory Deficits and Neuronal Stunting after Early-Life Adversity

Early-life adversity (ELA) is associated with lifelong memory deficits, yet the responsible mechanisms remain unclear. We impose ELA by rearing rat pups in simulated poverty, assess hippocampal memory, and probe changes in gene expression, their transcriptional regulation, and the consequent changes...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Rep
Κύριοι συγγραφείς: Bolton, Jessica L., Schulmann, Anton, Garcia-Curran, Megan M., Regev, Limor, Chen, Yuncai, Kamei, Noriko, Shao, Manlin, Singh-Taylor, Akanksha, Jiang, Shan, Noam, Yoav, Molet, Jenny, Mortazavi, Ali, Baram, Tallie Z.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2020
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817243/
https://ncbi.nlm.nih.gov/pubmed/33326786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108511
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