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Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
Skin epithelium can accumulate a high burden of oncogenic mutations without morphological or functional consequences. To investigate the mechanism of oncogenic tolerance, we induced Hras(G12V) in single murine epidermal cells and followed them long term. We observed that Hras(G12V) promotes an early...
Gorde:
| Argitaratua izan da: | eLife |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
eLife Sciences Publications, Ltd
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7817173/ https://ncbi.nlm.nih.gov/pubmed/33393458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54618 |
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