PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain

Defense of the central nervous system (CNS) against infection must be accomplished without generation of potentially injurious immune cell-mediated or off-target inflammation which could impair key functions. As the CNS is an immune-privileged compartment, inducible innate defense mechanisms endogen...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lee, Ernest Y., Chan, Liana C., Wang, Huiyuan, Lieng, Juelline, Hung, Mandy, Srinivasan, Yashes, Wang, Jennifer, Waschek, James A., Ferguson, Andrew L., Lee, Kuo-Fen, Yount, Nannette Y., Yeaman, Michael R., Wong, Gerard C. L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2021
Sujets:
Physical Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817161/
https://ncbi.nlm.nih.gov/pubmed/33372152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917623117
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