PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain

Defense of the central nervous system (CNS) against infection must be accomplished without generation of potentially injurious immune cell-mediated or off-target inflammation which could impair key functions. As the CNS is an immune-privileged compartment, inducible innate defense mechanisms endogen...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lee, Ernest Y., Chan, Liana C., Wang, Huiyuan, Lieng, Juelline, Hung, Mandy, Srinivasan, Yashes, Wang, Jennifer, Waschek, James A., Ferguson, Andrew L., Lee, Kuo-Fen, Yount, Nannette Y., Yeaman, Michael R., Wong, Gerard C. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
Onderwerpen:
Physical Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817161/
https://ncbi.nlm.nih.gov/pubmed/33372152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917623117
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