Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defen...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Khakzad, Hamed, Happonen, Lotta, Karami, Yasaman, Chowdhury, Sounak, Bergdahl, Gizem Ertürk, Nilges, Michael, Tran Van Nhieu, Guy, Malmström, Johan, Malmström, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817036/
https://ncbi.nlm.nih.gov/pubmed/33411763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008169
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