Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations

Mechanisms that control nuclear membrane remodeling are essential to maintain the integrity of the nucleus but remain to be fully defined. Here, we identify a phosphatidic acid (PA)–binding capacity in the nuclear envelope (NE)–specific ESCRT, Chm7, in budding yeast. Chm7’s interaction with PA-rich...

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Publicado en:J Cell Biol
Main Authors: Thaller, David J., Tong, Danqing, Marklew, Christopher J., Ader, Nicholas R., Mannino, Philip J., Borah, Sapan, King, Megan C., Ciani, Barbara, Lusk, C. Patrick
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816628/
https://ncbi.nlm.nih.gov/pubmed/33464310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004222
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