Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations

Mechanisms that control nuclear membrane remodeling are essential to maintain the integrity of the nucleus but remain to be fully defined. Here, we identify a phosphatidic acid (PA)–binding capacity in the nuclear envelope (NE)–specific ESCRT, Chm7, in budding yeast. Chm7’s interaction with PA-rich...

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Publicat a:J Cell Biol
Autors principals: Thaller, David J., Tong, Danqing, Marklew, Christopher J., Ader, Nicholas R., Mannino, Philip J., Borah, Sapan, King, Megan C., Ciani, Barbara, Lusk, C. Patrick
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816628/
https://ncbi.nlm.nih.gov/pubmed/33464310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004222
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