PCR-based genotyping assays to detect germline APC variant associated with hereditary gastrointestinal polyposis in Jack Russell terriers

BACKGROUND: The prevalence of gastrointestinal (GI) neoplastic polyps in Jack Russell terriers (JRTs) has increased in Japan since the late 2000s. Recently, we demonstrated that JRTs with GI polyps harbor identical germline variant in the APC gene (c.[462_463delinsTT]) in the heterozygous state. Thu...

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Publicado en:BMC Vet Res
Autores principales: Yoshizaki, Kyoko, Hirata, Akihiro, Matsushita, Hiroyuki, Nishii, Naohito, Kawabe, Mifumi, Mori, Takashi, Sakai, Hiroki
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814721/
https://ncbi.nlm.nih.gov/pubmed/33461531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02731-7
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