PCR-based genotyping assays to detect germline APC variant associated with hereditary gastrointestinal polyposis in Jack Russell terriers

BACKGROUND: The prevalence of gastrointestinal (GI) neoplastic polyps in Jack Russell terriers (JRTs) has increased in Japan since the late 2000s. Recently, we demonstrated that JRTs with GI polyps harbor identical germline variant in the APC gene (c.[462_463delinsTT]) in the heterozygous state. Thu...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Yoshizaki, Kyoko, Hirata, Akihiro, Matsushita, Hiroyuki, Nishii, Naohito, Kawabe, Mifumi, Mori, Takashi, Sakai, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814721/
https://ncbi.nlm.nih.gov/pubmed/33461531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02731-7
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