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Reliability of genomic variants across different next-generation sequencing platforms and bioinformatic processing pipelines

BACKGROUND: Next Generation Sequencing (NGS) is the fundament of various studies, providing insights into questions from biology and medicine. Nevertheless, integrating data from different experimental backgrounds can introduce strong biases. In order to methodically investigate the magnitude of sys...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Weißbach, Stephan, Sys, Stanislav, Hewel, Charlotte, Todorov, Hristo, Schweiger, Susann, Winter, Jennifer, Pfenninger, Markus, Torkamani, Ali, Evans, Doug, Burger, Joachim, Everschor-Sitte, Karin, May-Simera, Helen Louise, Gerber, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814447/
https://ncbi.nlm.nih.gov/pubmed/33468057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-07362-8
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