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Diffusion kurtosis imaging detects subclinical white matter abnormalities in Phenylketonuria

OBJECTIVE: Phenylketonuria (PKU) is an autosomal recessive disorder whereby deficiencies in phenylalanine metabolism cause progressive neurological dysfunction. Managing PKU is challenging, with disease monitoring focussed on short-term phenylalanine control rather than measures of neuronal damage....

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Bibliografiske detaljer
Udgivet i:Neuroimage Clin
Main Authors: Hellewell, Sarah C., Welton, Thomas, Eisenhuth, Kate, Tchan, Michel C., Grieve, Stuart M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814191/
https://ncbi.nlm.nih.gov/pubmed/33461111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102555
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