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DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life

Synthetic glucocorticoids (sGC) are administered to women at risk of preterm delivery, approximately 10% of all pregnancies. In animal models, offspring exposed to elevated glucocorticoids, either by administration of sGC or endogenous glucocorticoids as a result of maternal stress, show increased r...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Sasaki, Aya, Eng, Margaret E., Lee, Abigail H., Kostaki, Alisa, Matthews, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813870/
https://ncbi.nlm.nih.gov/pubmed/33462183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01186-6
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