Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis

Germinal centers (GC) are sites for extensive B cell proliferation and homeostasis is maintained by programmed cell death. The complement regulatory protein Decay Accelerating Factor (DAF) blocks complement deposition on host cells and therefore also phagocytosis of cells. Here, we show that B cells...

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Vydáno v:Front Immunol
Hlavní autoři: Dernstedt, Andy, Leidig, Jana, Holm, Anna, Kerkman, Priscilla F., Mjösberg, Jenny, Ahlm, Clas, Henriksson, Johan, Hultdin, Magnus, Forsell, Mattias N. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813799/
https://ncbi.nlm.nih.gov/pubmed/33469456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.599647
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