Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis

Germinal centers (GC) are sites for extensive B cell proliferation and homeostasis is maintained by programmed cell death. The complement regulatory protein Decay Accelerating Factor (DAF) blocks complement deposition on host cells and therefore also phagocytosis of cells. Here, we show that B cells...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Dernstedt, Andy, Leidig, Jana, Holm, Anna, Kerkman, Priscilla F., Mjösberg, Jenny, Ahlm, Clas, Henriksson, Johan, Hultdin, Magnus, Forsell, Mattias N. E.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813799/
https://ncbi.nlm.nih.gov/pubmed/33469456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.599647
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