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Inducible nuclear import by TetR aptamer-controlled 3′ splice site selection
Correct cellular localization is essential for the function of many eukaryotic proteins and hence cell physiology. Here, we present a synthetic genetic device that allows the control of nuclear and cytosolic localization based on controlled alternative splicing in human cells. The device is based on...
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| Publicado no: | RNA |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812871/ https://ncbi.nlm.nih.gov/pubmed/33148600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.077453.120 |
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