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Robust gene expression control in human cells with a novel universal TetR aptamer splicing module

Fine-tuning of gene expression is desirable for a wide range of applications in synthetic biology. In this context, RNA regulatory devices provide a powerful and highly functional tool. We developed a versatile, robust and reversible device to control gene expression by splicing regulation in human...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Mol, Adam A, Groher, Florian, Schreiber, Britta, Rühmkorff, Ciaran, Suess, Beatrix
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846422/
https://ncbi.nlm.nih.gov/pubmed/31504742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz753
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