Single-cell transcriptomic analysis reveals the immune landscape of lung in steroid-resistant asthma exacerbation

Exaggerated airway hyperresponsiveness and inflammation are hallmarks of asthma, and lipopolysaccharide (LPS) exposure is linked to the severity of the disease and steroid resistance. To investigate the mechanisms underlying asthma exacerbation, we established a mouse model of LPS-induced steroid-re...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Lingli, Netto, Keilah G., Zhou, Lujia, Liu, Xiaojie, Wang, Ming, Zhang, Guojun, Foster, Paul S., Li, Fuguang, Yang, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812791/
https://ncbi.nlm.nih.gov/pubmed/33397719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005590118
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