Single-cell transcriptomic analysis reveals the immune landscape of lung in steroid-resistant asthma exacerbation

Exaggerated airway hyperresponsiveness and inflammation are hallmarks of asthma, and lipopolysaccharide (LPS) exposure is linked to the severity of the disease and steroid resistance. To investigate the mechanisms underlying asthma exacerbation, we established a mouse model of LPS-induced steroid-re...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Wang, Lingli, Netto, Keilah G., Zhou, Lujia, Liu, Xiaojie, Wang, Ming, Zhang, Guojun, Foster, Paul S., Li, Fuguang, Yang, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812791/
https://ncbi.nlm.nih.gov/pubmed/33397719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005590118
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