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The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans

Carbohydrates — namely glycans — decorate every cell in the human body and most secreted proteins. Advances in genomics, glycoproteomics and tools from chemical biology have made glycobiology more tractable and understandable. Dysregulated glycosylation plays a major role in disease processes from i...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Smith, Benjamin A. H., Bertozzi, Carolyn R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812346/
https://ncbi.nlm.nih.gov/pubmed/33462432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-00093-1
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