COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type‐2 and PDE4 gene expression in sputum

Chronic obstructive pulmonary disease (COPD) patients with higher eosinophil counts are associated with increased clinical response to phosphodiesterase‐4‐inhibitors (PDE4i). However, the underlying inflammatory mechanisms associated with this increased response is not yet elucidated. This post hoc...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Singh, Dave, Bassi, Michele, Balzano, Deborah, Lucci, Germano, Emirova, Aida, Anna Nandeuil, Marie, Jellema, Gera, Afolabi, Ebenezer K., Leaker, Brian, Kornmann, Oliver, Michael Beeh, Kai, Watz, Henrik, Govoni, Mirco
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812250/
https://ncbi.nlm.nih.gov/pubmed/33295083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16146
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