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Mechanical stimuli and matrix properties modulate cancer spheroid growth in three-dimensional gelatin culture

Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer cells thrive in this envir...

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Detalles Bibliográficos
Publicado en:J R Soc Interface
Main Authors: Curtis, Kimberly J., Schiavi, Jessica, Mc Garrigle, Myles J., Kumar, Vatsal, McNamara, Laoise M., Niebur, Glen L.
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811591/
https://ncbi.nlm.nih.gov/pubmed/33323051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0568
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