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The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids

Osteogenesis of mesenchymal stem cells (MSC) can be regulated by the mechanical environment. MSCs grown in 3D spheroids (mesenspheres) have preserved multi-lineage potential, improved differentiation efficiency, and exhibit enhanced osteogenic gene expression and matrix composition in comparison to...

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Bibliografske podrobnosti
izdano v:J Biomech
Main Authors: Griffin, F.E., Schiavi, J., McDevitt, T.C., McGarry, J.P., McNamara, L.M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392184/
https://ncbi.nlm.nih.gov/pubmed/28577903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2017.05.014
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