Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants: two clinical trials

BACKGROUND: Continued emergence and spread of circulating vaccine-derived type 2 polioviruses and vaccine-associated paralytic poliomyelitis from Sabin oral poliovirus vaccines (OPVs) has stimulated development of two novel type 2 OPV candidates (OPV2-c1 and OPV2-c2) designed to have similar immunog...

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Pubblicato in:Lancet
Autori principali: Sáez-Llorens, Xavier, Bandyopadhyay, Ananda S, Gast, Christopher, Leon, Tirza De, DeAntonio, Rodrigo, Jimeno, Jose, Caballero, Maria Isabel, Aguirre, Gabriela, Oberste, M Steven, Weldon, William C, Konopka-Anstadt, Jennifer L, Modlin, John, Bachtiar, Novilia S, Fix, Alan, Konz, John, Clemens, Ralf, Costa Clemens, Sue Ann, Rüttimann, Ricardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811205/
https://ncbi.nlm.nih.gov/pubmed/33308427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(20)32540-X
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