Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials

BACKGROUND: Two novel type 2 oral poliovirus vaccine (OPV2) candidates, novel OPV2-c1 and novel OPV2-c2, designed to be more genetically stable than the licensed Sabin monovalent OPV2, have been developed to respond to ongoing polio outbreaks due to circulating vaccine-derived type 2 polioviruses. M...

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Publicado no:Lancet
Main Authors: De Coster, Ilse, Leroux-Roels, Isabel, Bandyopadhyay, Ananda S, Gast, Christopher, Withanage, Kanchanamala, Steenackers, Katie, De Smedt, Philippe, Aerssens, Annelies, Leroux-Roels, Geert, Oberste, M Steven, Konopka-Anstadt, Jennifer L, Weldon, William C, Fix, Alan, Konz, John, Wahid, Rahnuma, Modlin, John, Clemens, Ralf, Costa Clemens, Sue Ann, Bachtiar, Novilia S, Van Damme, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811203/
https://ncbi.nlm.nih.gov/pubmed/33308429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(20)32541-1
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