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Sensitization of ovarian tumor to immune checkpoint blockade by boosting senescence-associated secretory phenotype
Therapy-induced senescence-associated secretory phenotype (SASP) correlates with overcoming resistance to immune checkpoint blockade (ICB). Intrinsic resistance to ICB is a major clinical challenge. For example, ovarian cancer is largely resistant to ICB. Here we show that adoptive transfer of SASP-...
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| Publicat a: | iScience |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7811168/ https://ncbi.nlm.nih.gov/pubmed/33490922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.102016 |
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