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Sarcolipin alters SERCA1a interdomain communication by impairing binding of both calcium and ATP
Sarcolipin (SLN), a single-spanning membrane protein, is a regulator of the sarco-endoplasmic reticulum Ca(2+)-ATPase (SERCA1a). Chemically synthesized SLN, palmitoylated or not (pSLN or SLN), and recombinant wild-type rabbit SERCA1a expressed in S. cerevisiae design experimental conditions that pro...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810697/ https://ncbi.nlm.nih.gov/pubmed/33452371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81061-6 |
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