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Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice
Spinal cord injury (SCI) often causes severe and permanent disabilities due to the regenerative failure of severed axons. Here we report significant locomotor recovery of both hindlimbs after a complete spinal cord crush. This is achieved by the unilateral transduction of cortical motoneurons with a...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810685/ https://ncbi.nlm.nih.gov/pubmed/33452250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20112-4 |
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