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Promotion of Functional Nerve Regeneration by Inhibition of Microtubule Detyrosination

Functional recovery of injured peripheral neurons often remains incomplete, but the clinical outcome can be improved by increasing the axonal growth rate. Adult transgenic GSK3α(S/A)/β(S/A) knock-in mice with sustained GSK3 activity show markedly accelerated sciatic nerve regeneration. Here, we unra...

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書目詳細資料
發表在:J Neurosci
Main Authors: Gobrecht, Philipp, Andreadaki, Anastasia, Diekmann, Heike, Heskamp, Annemarie, Leibinger, Marco, Fischer, Dietmar
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705512/
https://ncbi.nlm.nih.gov/pubmed/27053198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4486-15.2016
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