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Promotion of Functional Nerve Regeneration by Inhibition of Microtubule Detyrosination

Functional recovery of injured peripheral neurons often remains incomplete, but the clinical outcome can be improved by increasing the axonal growth rate. Adult transgenic GSK3α(S/A)/β(S/A) knock-in mice with sustained GSK3 activity show markedly accelerated sciatic nerve regeneration. Here, we unra...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gobrecht, Philipp, Andreadaki, Anastasia, Diekmann, Heike, Heskamp, Annemarie, Leibinger, Marco, Fischer, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705512/
https://ncbi.nlm.nih.gov/pubmed/27053198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4486-15.2016
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