Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss

Bone is maintained by coupled activities of bone-forming osteoblasts/osteocytes and bone-resorbing osteoclasts. Alterations in this relationship can lead to pathologic bone loss such as osteoporosis. It is well known that osteogenic cells support osteoclastogenesis via production of RANKL. Interesti...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Yu, Wei, Zhong, Leilei, Yao, Lutian, Wei, Yulong, Gui, Tao, Li, Ziqing, Kim, Hyunsoo, Holdreith, Nicholas, Jiang, Xi, Tong, Wei, Dyment, Nathaniel, Liu, X. Sherry, Yang, Shuying, Choi, Yongwon, Ahn, Jaimo, Qin, Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810488/
https://ncbi.nlm.nih.gov/pubmed/33206630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140214
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