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Oleic acid restores suppressive defects in tissue-resident FOXP3 Tregs from patients with multiple sclerosis
FOXP3(+) Tregs rely on fatty acid β-oxidation–driven (FAO-driven) oxidative phosphorylation (OXPHOS) for differentiation and function. Recent data demonstrate a role for Tregs in the maintenance of tissue homeostasis, with tissue-resident Tregs possessing tissue-specific transcriptomes. However, spe...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810477/ https://ncbi.nlm.nih.gov/pubmed/33170805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138519 |
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