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Pathway crosstalk effects: Shrinkage and disentanglement using a Bayesian hierarchical model

Identifying the biological pathways that are related to various clinical phenotypes is an important concern in biomedical research. Based on estimated expression levels and/or p-values, over-representation analysis (ORA) methods provide rankings of pathways, but they are tainted because pathways ove...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stat Biosci
Egile Nagusiak: TOMOIAGA, ALIN, WESTFALL, PETER, DONATO, MICHELE, DRAGHICI, SORIN, HASSAN, SONIA, ROMERO, ROBERTO, TELLAROLI, PAOLA
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810237/
https://ncbi.nlm.nih.gov/pubmed/33456621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-016-9160-1
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