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Pancreas-specific deletion of protein kinase D attenuates inflammation, necrosis, and severity of acute pancreatitis

BACKGROUND: Protein kinase D (PKD) family, which includes PKD/PKD1, PKD2, and PKD3, has been increasingly implicated in the regulation of multiple cellular functions and human diseases. We recently reported that pharmacologic inhibition of PKD ameliorated the pathologic responses and severity of pan...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Basis Dis
Main Authors: Yuan, Jingzhen, Chheda, Chintan, Piplani, Honit, Geng, Meng, Tan, Grace, Thakur, Reetu, Pandol, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810170/
https://ncbi.nlm.nih.gov/pubmed/33039594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2020.165987
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