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Pancreas-specific deletion of protein kinase D attenuates inflammation, necrosis, and severity of acute pancreatitis

BACKGROUND: Protein kinase D (PKD) family, which includes PKD/PKD1, PKD2, and PKD3, has been increasingly implicated in the regulation of multiple cellular functions and human diseases. We recently reported that pharmacologic inhibition of PKD ameliorated the pathologic responses and severity of pan...

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Bibliografiset tiedot
Julkaisussa:Biochim Biophys Acta Mol Basis Dis
Päätekijät: Yuan, Jingzhen, Chheda, Chintan, Piplani, Honit, Geng, Meng, Tan, Grace, Thakur, Reetu, Pandol, Stephen J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810170/
https://ncbi.nlm.nih.gov/pubmed/33039594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2020.165987
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