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Phosphoproteomics reveals novel modes of function and inter‐relationships among PIKKs in response to genotoxic stress
The DNA damage response (DDR) is a complex signaling network that relies on cascades of protein phosphorylation, which are initiated by three protein kinases of the family of PI3‐kinase‐related protein kinases (PIKKs): ATM, ATR, and DNA‐PK. ATM is missing or inactivated in the genome instability syn...
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| Опубликовано в: : | EMBO J |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809795/ https://ncbi.nlm.nih.gov/pubmed/33215756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104400 |
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