Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

BACKGROUND: Tripterygium hypoglaucum Hutch (THH) both has prominent efficacy and unwarranted toxicity in the treatment of autoimmune diseases. Nevertheless, its pharmacological and toxicological profiles still remain to be elucidated. In the current study, the network pharmacology approach was appli...

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Vydáno v:BMC Complement Med Ther
Hlavní autoři: Zhang, Dan, Dong, Yizhu, Lv, Jintao, Zhang, Bing, Zhang, Xiaomeng, Lin, Zhijian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809745/
https://ncbi.nlm.nih.gov/pubmed/33446184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-021-03210-8
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