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Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

BACKGROUND: Tripterygium hypoglaucum Hutch (THH) both has prominent efficacy and unwarranted toxicity in the treatment of autoimmune diseases. Nevertheless, its pharmacological and toxicological profiles still remain to be elucidated. In the current study, the network pharmacology approach was appli...

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Publicat a:BMC Complement Med Ther
Autors principals: Zhang, Dan, Dong, Yizhu, Lv, Jintao, Zhang, Bing, Zhang, Xiaomeng, Lin, Zhijian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809745/
https://ncbi.nlm.nih.gov/pubmed/33446184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-021-03210-8
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