Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations

Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we kinetically and mechanistically describe the non-reducing-end xylose-releasing exo-oligoxylanase activity and report the crystal str...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Morais, Mariana A. B., Coines, Joan, Domingues, Mariane N., Pirolla, Renan A. S., Tonoli, Celisa C. C., Santos, Camila R., Correa, Jessica B. L., Gozzo, Fabio C., Rovira, Carme, Murakami, Mario T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809346/
https://ncbi.nlm.nih.gov/pubmed/33446650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20620-3
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