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SPECC1L-deficient primary mouse embryonic palatal mesenchyme cells show speed and directionality defects
Cleft lip and/or palate (CL/P) are common anomalies occurring in 1/800 live-births. Pathogenic SPECC1L variants have been identified in patients with CL/P, which signifies a primary role for SPECC1L in craniofacial development. Specc1l mutant mouse embryos exhibit delayed palatal shelf elevation acc...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809270/ https://ncbi.nlm.nih.gov/pubmed/33446878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81123-9 |
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