High blood flow shear stress values are associated with circulating tumor cells cluster disaggregation in a multi-channel microfluidic device

Metastasis represents a dynamic succession of events involving tumor cells which disseminate through the organism via the bloodstream. Circulating tumor cells (CTCs) can flow the bloodstream as single cells or as multicellular aggregates (clusters), which present a different potential to metastasize...

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Veröffentlicht in:PLoS One
Hauptverfasser: Marrella, Alessandra, Fedi, Arianna, Varani, Gabriele, Vaccari, Ivan, Fato, Marco, Firpo, Giuseppe, Guida, Patrizia, Aceto, Nicola, Scaglione, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808575/
https://ncbi.nlm.nih.gov/pubmed/33444361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245536
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