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Antibody-mediated delivery of LIGHT to the tumor boosts natural killer cells and delays tumor progression
LIGHT is a member of the tumor necrosis factor superfamily, which has been claimed to mediate anti-tumor activity on the basis of cancer cures observed in immunocompetent mice bearing transgenic LIGHT-expressing tumors. The preclinical development of a LIGHT-based therapeutic has been hindered by th...
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| Publicado no: | MAbs |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7808322/ https://ncbi.nlm.nih.gov/pubmed/33404287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1868066 |
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