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Glutamate Dehydrogenase: Structure, Allosteric Regulation, and Role in Insulin Homeostasis
Glutamate dehydrogenase (GDH) is a homohexameric enzyme that catalyzes the reversible oxidative deamination of l-glutamate to 2-oxoglutarate. Only in the animal kingdom is this enzyme heavily allosterically regulated by a wide array of metabolites. The major activators are ADP and leucine and inhibi...
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| Veröffentlicht in: | Neurochem Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7808316/ https://ncbi.nlm.nih.gov/pubmed/24122080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-013-1173-2 |
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