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Targeting metabolism to reverse T‐cell exhaustion in chronic viral infections

CD8 T‐cells are an essential component of the adaptive immune response accountable for the clearance of virus‐infected cells via cytotoxic effector functions. Maintaining a specific metabolic profile is necessary for these T‐cells to sustain their effector functions and clear pathogens. When CD8 T‐c...

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Publicado en:Immunology
Autores principales: Sears, John D., Waldron, Kevin J., Wei, Jian, Chang, Chih‐Hao
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808153/
https://ncbi.nlm.nih.gov/pubmed/32681647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13238
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