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Targeting metabolism to reverse T‐cell exhaustion in chronic viral infections

CD8 T‐cells are an essential component of the adaptive immune response accountable for the clearance of virus‐infected cells via cytotoxic effector functions. Maintaining a specific metabolic profile is necessary for these T‐cells to sustain their effector functions and clear pathogens. When CD8 T‐c...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Sears, John D., Waldron, Kevin J., Wei, Jian, Chang, Chih‐Hao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808153/
https://ncbi.nlm.nih.gov/pubmed/32681647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13238
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