Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells

BACKGROUND: Osteosarcoma (OS) is a malignant tumor of the bone mostly observed in children and adolescents. The current treatment approach includes neoadjuvant and adjuvant chemotherapy; however, drug resistance often hinders therapy in OS patients. Also, the post-relapse survival of OS patients is...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Saini, Heena, Sharma, Harshita, Mukherjee, Sudeshna, Chowdhury, Shibasish, Chowdhury, Rajdeep
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807844/
https://ncbi.nlm.nih.gov/pubmed/33446200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01720-y
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