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The dynamic role of autophagy and MAPK signaling in determining cell fate under cisplatin stress in osteosarcoma cells

Osteosarcoma (OS) is an aggressive bone malignancy commonly observed in children and adolescents. Sub-optimal therapy for years has irretrievably compromised the chances of OS patient survival; also, lack of extensive research on this rare disease has hindered therapeutic development. Cisplatin, a c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mukherjee, Sudeshna, Dash, Subhra, Lohitesh, K., Chowdhury, Rajdeep
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466322/
https://ncbi.nlm.nih.gov/pubmed/28598976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179203
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